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Human alpha-1 antitrypsin Pittsburgh (M358R/C232S) recombinant bacterial expression. This protein has an N-terminal His tag. The Pittsburgh mutation (M358R) turns antitrypsin into a potent inhibitor or thrombin. The C232S mutation prevents oxidation of this residue, including disulphide bond formation.
Species: Human
Source: Recombinant
Expression: Bacterial
Cell Line: E coli
Sequence Type: Mutant
SKUs: 10250, 10249
Human alpha-1 antitrypsin Pittsburgh (M358R/C232S) recombinant bacterial expression. This protein has an N-terminal His tag. The Pittsburgh mutation (M358R) turns antitrypsin into a potent inhibitor or thrombin. The C232S mutation prevents oxidation of this residue, including disulphide bond formation.
Molecular Weight: 45,503
Conjugate: His Tag
UniProt:P01009
Synonyms: Antitrypsin Pittsburgh, AT Pitts, A1AT Pitts, α-1 AT Pitts, SERPINA1
Residues: 26-418 (2-394 Mature numbering)
| Weight | 0.1 milligram, 1 milligram |
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